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30 March 2020 Quantitative 3D fluorescence diffuse optical tomography with 3D ultrasound imaging registration in small animal study
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Abstract
An innovative dual-modality 3D fluorescence/3D ultrasound tomography system was demonstrated in this research. The system includes an electron-multiplying charge-coupled device (EMCCD), a 660 nm wavelength fiber-coupling laser, and a 10-15 MHz frequency customized single-element ultrasound transducer on a 3D rotating scanning device. We combined multiple ultrasound images from different sections to obtain a whole-body 3D mesh of mice, which provide anatomical information. In this study, we demonstrated the accuracy of this system through a 4T1 tumor-bearing nude mice experiment.
Conference Presentation
© (2020) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Chen-Yu Liu, Shih-Po Su, Pei-An Lo, and Hui-Hua Kenny Chiang "Quantitative 3D fluorescence diffuse optical tomography with 3D ultrasound imaging registration in small animal study", Proc. SPIE 11351, Unconventional Optical Imaging II, 113511M (30 March 2020); https://doi.org/10.1117/12.2555445
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