Wearable laser Doppler flowmetry for the analysis of microcirculatory changes during intravenous infusion in patients with diabetes mellitus

Elena V. Zharkikh; Yulia I. Loktionova; Igor O. Kozlov; Angelina I. Zherebtsova; Victor V. Sidorov; Evgeny A. Zherebtsov; Andrey V. Dunaev; Edik U. Rafailov

doi:10.1117/12.2552464

2 April 2020 Wearable laser Doppler flowmetry for the analysis of microcirculatory changes during intravenous infusion in patients with diabetes mellitus

Elena V. Zharkikh, Yulia I. Loktionova, Igor O. Kozlov, Angelina I. Zherebtsova, Victor V. Sidorov, Evgeny A. Zherebtsov, Andrey V. Dunaev, Edik U. Rafailov

Author Affiliations +

Proceedings Volume 11363, Tissue Optics and Photonics; 113631K (2020) https://doi.org/10.1117/12.2552464
Event: SPIE Photonics Europe, 2020, Online Only

Abstract

The article is aimed at conducting pilot studies of microcirculation changes in patients with diabetes mellitus during the course of intravenous infusions of alpha lipoic acid. The study was conducted with patients with diabetes during the passage of a standard course of treatment. The change in parameters was compared before the start of the infusion course, during and after the course. A system of wearable laser Doppler monitors was used to conduct the study. The study showed that although the microcirculation index does not undergo significant changes during the treatment process, spectral analysis of the recorded signal has potential applicability. Further studies with a larger sample group are required for a qualitative analysis of the observed effects.

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Elena V. Zharkikh, Yulia I. Loktionova, Igor O. Kozlov, Angelina I. Zherebtsova, Victor V. Sidorov, Evgeny A. Zherebtsov, Andrey V. Dunaev, and Edik U. Rafailov "Wearable laser Doppler flowmetry for the analysis of microcirculatory changes during intravenous infusion in patients with diabetes mellitus", Proc. SPIE 11363, Tissue Optics and Photonics, 113631K (2 April 2020); https://doi.org/10.1117/12.2552464

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