Full-size anthropomorphic phantom for 2D and 3D breast x-ray imaging

James G. Mainprize; Gordon E. Mawdsley; Ann-Katherine Carton; Zhijin Li; Remy Klausz; Serge Muller; Martin J. Yaffe

doi:10.1117/12.2560358

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22 May 2020 Full-size anthropomorphic phantom for 2D and 3D breast x-ray imaging

James G. Mainprize, Gordon E. Mawdsley, Ann-Katherine Carton, Zhijin Li, Remy Klausz, Serge Muller, Martin J. Yaffe

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Proceedings Volume 11513, 15th International Workshop on Breast Imaging (IWBI2020); 1151302 (2020) https://doi.org/10.1117/12.2560358
Event: Fifteenth International Workshop on Breast Imaging, 2020, Leuven, Belgium

Abstract

Anthropomorphic breast phantoms are used to create images that mimic aspects of clinical breast images and are useful in optimization and characterization of breast imaging systems. Here, a full-sized compressed physical breast phantom is designed and manufactured with 100 m resolution, high reproducibility and x-ray properties similar to that of breast tissues. The phantom design is based on a digital model derived from the morphology and distribution of large, medium and small scale fibroglandular and inter-glandular adipose tissue observed in clinical breast computerized tomography (bCT) images. The physical phantom consists of four slabs of a polyamide-12 component that mimics adipose tissue fabricated using selective laser sintering (SLS). The fibroglandular component is a low viscosity resin doped with a small amount of zinc oxide nanoparticles (<110 nm) to increase attenuation. The phantom was imaged on a Senographe Pristina and compared to image simulations of the virtual phantom. The power spectral parameter, β was 3.8±0.2 and 3.9±0.5 for the physical and virtual phantoms in a digital mammogram. The corresponding Laplacian fractional entropy (LFE) averaged 0.22 and 0.14 across the range 0.125–1.29 mm^-1. Very good texture cancellation was obtained in contrast-enhanced spectral mammography.

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James G. Mainprize, Gordon E. Mawdsley, Ann-Katherine Carton, Zhijin Li, Remy Klausz, Serge Muller, and Martin J. Yaffe "Full-size anthropomorphic phantom for 2D and 3D breast x-ray imaging", Proc. SPIE 11513, 15th International Workshop on Breast Imaging (IWBI2020), 1151302 (22 May 2020); https://doi.org/10.1117/12.2560358

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