CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume 11553 > Article
Presentation
10 October 2020 Dynamic study of three-dimensional peroxynitrite flux in epileptic brain using high-speed and high-resolution photoacoustic imaging
Yaguang Ren, Chengbo Liu
Author Affiliations +
Proceedings Volume 11553, Optics in Health Care and Biomedical Optics X; 115530K (2020) https://doi.org/10.1117/12.2573357
Event: SPIE/COS Photonics Asia, 2020, Online Only
Abstract
In this study, we proposed the linear array ultrasound transducer based photoacoustic imaging (PAI) method for peroxynitrite flux study when having Epilepsy. To our best knowledge, this is the first study using high-speed and high-resolution imaging system that can achieve study of the dynamic flux of peroxynitrite in the whole brain. A novel PAI probe was designed based on high frequency linear array ultrasound transducer for high-resolution brain imaging. Sparse sampling based compressed sensing combined with arc-rotary scanning strategy was proposed to achieve high speed PAI of the whole Brain. A mice epileptic model was established, which was continuously monitored for the dynamic flux of peroxynitrite within the brain using a peroxynitrite sensitive photoacoustic probe: Manganese (II) Texaphyrin (MMn). The dynamic neurochemical mechanisms in the process of epileptic seizure was investigated and the correlation between epilepsy burst and severe neuron injury was explored.
Conference Presentation
© (2020) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Yaguang Ren and Chengbo Liu "Dynamic study of three-dimensional peroxynitrite flux in epileptic brain using high-speed and high-resolution photoacoustic imaging", Proc. SPIE 11553, Optics in Health Care and Biomedical Optics X, 115530K (10 October 2020); https://doi.org/10.1117/12.2573357
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
;
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 PRESENTATION
WATCH
PRESENTATION SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
KEYWORDS
Epilepsy
Brain
Neuroimaging
Photoacoustic imaging
3D image processing
Pathogens
Transducers
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top