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X-ray phase imaging has found limited clinical use due to requirements on x-ray coherence that may not be easily translated to clinical practice. Instead, this work employs a conventional source to create structured illumination with a simple wire mesh. The system has been employed to produce high contrast absorption images with simultaneous differential phase contrast images. In previous work we have demonstrated accurate quantitative phase extraction. In this work, we have incorporated the dark field information to successfully reveal additional structure in low contrast objects.
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Uttam Pyakurel, Desirée D'Moore, Pikting Cheung, Bushra Kanwal, Xiaoyun Zhang, C. A. MacDonald, Jonathan C. Petruccelli, "Incorporating dark-field information in mesh-based x-ray phase imaging," Proc. SPIE 11595, Medical Imaging 2021: Physics of Medical Imaging, 115951M (15 February 2021); https://doi.org/10.1117/12.2582192