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Two quantitative methods were used to determine high-temporal resolution velocity changes throughout HSA image sequences, one based on movements of discrete radiopaque microspheres and the other on iodinated contrast injections. The chosen pump settings encompassed a wide range of flow situations, all of which produced unique velocity measurements over the flow duration as captured by the detector. Variations in velocity are illustrated due to both the cyclic action of the pump and various phantom morphologies. These HSA methods can be applied to derive a wide range of velocity distributions, which may be used to further quantify important hemodynamic parameters.
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A. Shields, S. V. Setlur Nagesh, C. Ionita, D. R. Bednarek, S. Rudin, "Characterization of velocity patterns produced by pulsatile and constant flows using 1000 fps high-speed angiography (HSA)," Proc. SPIE 11600, Medical Imaging 2021: Biomedical Applications in Molecular, Structural, and Functional Imaging, 116001G (15 February 2021); https://doi.org/10.1117/12.2580888