In vivo optical characterization of middle ear effusions associated with otitis media

Jungeun Won; Guillermo L. Monroy; Ryan G. Porter; Michael A. Novak; Ronit Barkalifa; Darold R. Spillman Jr.; Edita Aksamitiene; Eric J. Chaney; Stephen A. Boppart

doi:10.1117/12.2577278

5 March 2021 In vivo optical characterization of middle ear effusions associated with otitis media

Jungeun Won, Guillermo L. Monroy, Ryan G. Porter, Michael A. Novak, Ronit Barkalifa, Darold R. Spillman Jr., Edita Aksamitiene, Eric J. Chaney, Stephen A. Boppart

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Proceedings Volume 11627, Photonic Therapeutics and Diagnostics in Dentistry, Head and Neck Surgery, and Otolaryngology; 116270A (2021) https://doi.org/10.1117/12.2577278
Event: SPIE BiOS, 2021, Online Only

Abstract

Middle ear effusions (MEEs) are accumulated middle ear secretions or fluid behind the eardrum during otitis media (OM). A portable, handheld OCT system was developed to non-invasively investigate various optical scattering properties of MEEs in pediatric subjects. Furthermore, clinically relevant parameters of MEEs, including viscosity and bacterial load, were measured from the extracted MEEs after the surgical procedure to treat OM. In vivo OCT images of the middle ear prior to the surgery, OCT images of the extracted MEEs, and biological parameters were correlated to determine the relationship between the optical signatures in MEEs and the clinical findings of OM.

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Jungeun Won, Guillermo L. Monroy, Ryan G. Porter, Michael A. Novak, Ronit Barkalifa, Darold R. Spillman Jr., Edita Aksamitiene, Eric J. Chaney, and Stephen A. Boppart "In vivo optical characterization of middle ear effusions associated with otitis media", Proc. SPIE 11627, Photonic Therapeutics and Diagnostics in Dentistry, Head and Neck Surgery, and Otolaryngology, 116270A (5 March 2021); https://doi.org/10.1117/12.2577278

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KEYWORDS

Ear

In vivo imaging

Optical coherence tomography

Surgery

Biomedical optics

Diagnostics

Proteins

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