Functional diffuse correlation spectroscopy measurements on cognitively healthy and mild cognitive impaired populations during single and dual motor tasks

Stella Avtzi; Cristina Udina; Miriam Mota; Carmina Castellano-Tejedor; Luis Soto-Bagaria; Marco Inzitari; Turgut Durduran; Veronika Parfentyeva

doi:10.1117/12.2583129

5 March 2021 Functional diffuse correlation spectroscopy measurements on cognitively healthy and mild cognitive impaired populations during single and dual motor tasks

Stella Avtzi, Cristina Udina, Miriam Mota, Carmina Castellano-Tejedor, Luis Soto-Bagaria, Marco Inzitari, Turgut Durduran, Veronika Parfentyeva

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Proceedings Volume 11639, Optical Tomography and Spectroscopy of Tissue XIV; 116391H (2021) https://doi.org/10.1117/12.2583129
Event: SPIE BiOS, 2021, Online Only

Abstract

Functional diffuse correlation spectroscopy was used during various attention-demanding motor tasks, and test whether cerebral blood flow (CBF) changes differentiate between age groups or are related to mild cognitive impairment (MCI). Sixty-nine subjects were measured during single (ST) and dual motor tasks (DT); seventeen Cognitively Healthy Younger (<65y.o.,CH-Y), sixteen Cognitively Healthy Older Adults (CH-O), fifteen subjects amnestic - MCI, single-domain (aMCI - SD) and twenty-one amnestic - MCI, multi-domain (aMCI - MD). Results show elevated CBF during cognitively demanding DT statistically different (p <0.001) from reference test. No statistical difference was observed between CH and aMCI subjects (p = 0.36).

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Stella Avtzi, Cristina Udina, Miriam Mota, Carmina Castellano-Tejedor, Luis Soto-Bagaria, Marco Inzitari, Turgut Durduran, and Veronika Parfentyeva "Functional diffuse correlation spectroscopy measurements on cognitively healthy and mild cognitive impaired populations during single and dual motor tasks", Proc. SPIE 11639, Optical Tomography and Spectroscopy of Tissue XIV, 116391H (5 March 2021); https://doi.org/10.1117/12.2583129

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