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5 March 2021 Preclinical cancer imaging using a multispectral LED-based photoacoustic and ultrasound imaging system
Marvin Xavierselvan, Mithun Kuniyil Ajith Singh, Srivalleesha Mallidi
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Proceedings Volume 11642, Photons Plus Ultrasound: Imaging and Sensing 2021; 116422G (2021) https://doi.org/10.1117/12.2579263
Event: SPIE BiOS, 2021, Online Only
Abstract
In this study, we evaluated the capability of an LED-based photoacoustic imaging system (AcousticX, 7MHz ultrasound probe, 850 nm LED arrays) in imaging heterogenous vasculature of subcutaneous tumors in mice. For evaluating the functional imaging capability, we used AcousticX with dual-wavelength LED arrays (750/850 nm) and monitored oxygen saturation of the tumor volume. We also compared the tumor images acquired by AcousticX and a commercial laser-based photoacoustic imaging system. Our results show that LED-based photoacoustic imaging can obtain similar imaging performance as a laser-based system and thus holds good promise in preclinical cancer research in an affordable setting.
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Marvin Xavierselvan, Mithun Kuniyil Ajith Singh, and Srivalleesha Mallidi "Preclinical cancer imaging using a multispectral LED-based photoacoustic and ultrasound imaging system", Proc. SPIE 11642, Photons Plus Ultrasound: Imaging and Sensing 2021, 116422G (5 March 2021); https://doi.org/10.1117/12.2579263
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KEYWORDS
Imaging systems
Multispectral imaging
Photoacoustic imaging
Ultrasonography
Cancer
Tumors
Preclinical imaging
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