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5 March 2021 Dual-modality photoacoustic remote sensing (PARS) microscopy and swept-source optical coherence tomography (SS-OCT) for in-vivo imaging
Zohreh Hosseinaee, Nima Abbasi, Alex Tummon Simmons, Layla Khalil, Kevan L. Bell, Parsin Haji Reza
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Proceedings Volume 11642, Photons Plus Ultrasound: Imaging and Sensing 2021; 1164232 (2021) https://doi.org/10.1117/12.2578036
Event: SPIE BiOS, 2021, Online Only
Abstract
A dual-modal optical imaging system combining photoacoustic remote sensing (PARS) and swept-source optical coherence tomography (SS-OCT) is presented. The PARS subsystem utilized a pulsed excitation beam at 532 nm confocal with a low-coherence interrogation beam centered at 830 nm to detect photoacoustic signals. The OCT subsystem employs a 1060 nm VCSEL swept source with a 60 kHz A-scan rate and 8 μm axial resolution in tissue. Volumetric images were acquired from carbon fibers and in-vivo biological tissues. To our knowledge, this is the first study demonstrating a combination of SS-OCT with optical-resolution photoacoustic microscopy for in-vivo, non-contact imaging of tissues.
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Zohreh Hosseinaee, Nima Abbasi, Alex Tummon Simmons, Layla Khalil, Kevan L. Bell, and Parsin Haji Reza "Dual-modality photoacoustic remote sensing (PARS) microscopy and swept-source optical coherence tomography (SS-OCT) for in-vivo imaging", Proc. SPIE 11642, Photons Plus Ultrasound: Imaging and Sensing 2021, 1164232 (5 March 2021); https://doi.org/10.1117/12.2578036
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KEYWORDS
Optical coherence tomography
In vivo imaging
Photoacoustic spectroscopy
Microscopy
Remote sensing
Tissue optics
Optical microscopy
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