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Non-invasive identification, understanding and evaluation of articular cartilage damage is paramount for osteoarthritis researcher and clinician alike. Using polarisation sensitive optical coherence tomography together with impact and creep load, we use a range of metrics including birefringence to detect early signs of cartilage degeneration and gain new insights into the physiology of joint tissues
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Frédérique Vanholsbeeck, Matthew Goodwin, Marie Klufts, Joshua Workman, Ashvin Thambyah, "Birefringence as a proxy for viscoelastic properties of cartilage using polarisation sensitive optical coherence tomography," Proc. SPIE 11645, Optical Elastography and Tissue Biomechanics VIII, 116450E (5 March 2021); https://doi.org/10.1117/12.2587181