Validation of optical coherence elastography to study frequency dependent behaviour of the vitreous humour

Magdalena Anna Urbanska; Sophia Areta Rodrigues; Frédérique Vanholsbeeck

doi:10.1117/12.2577967

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5 March 2021 Validation of optical coherence elastography to study frequency dependent behaviour of the vitreous humour

Magdalena Anna Urbanska, Sophia Areta Rodrigues, Frédérique Vanholsbeeck

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Proceedings Volume 11645, Optical Elastography and Tissue Biomechanics VIII; 1164518 (2021) https://doi.org/10.1117/12.2577967
Event: SPIE BiOS, 2021, Online Only

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Abstract

Optical Coherence Elastography (OCE) and a gold-standard method, oscillatory test, provide estimates of the shear modulus of a vitreous humour at different frequencies and are therefore impossible to compare. To reconcile these two methods, we investigated the frequency dependence of the shear modulus of a phantom of an extracted vitreous. The values obtained in the high frequency range with OCE were extrapolated and compared with the oscillatory test data for lower frequencies. The preliminary results show some discrepancy that might stem either from overestimation of the OCE data due to the wave excitation procedure or from a partially incomplete model.

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Magdalena Anna Urbanska, Sophia Areta Rodrigues, and Frédérique Vanholsbeeck "Validation of optical coherence elastography to study frequency dependent behaviour of the vitreous humour", Proc. SPIE 11645, Optical Elastography and Tissue Biomechanics VIII, 1164518 (5 March 2021); https://doi.org/10.1117/12.2577967

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