Miniaturization of an optical diffraction tomography system

Haojia Sun; Renjie Zhou

doi:10.1117/12.2583386

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5 March 2021 Miniaturization of an optical diffraction tomography system

Haojia Sun, Renjie Zhou

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Proceedings Volume 11653, Quantitative Phase Imaging VII; 116531M (2021) https://doi.org/10.1117/12.2583386
Event: SPIE BiOS, 2021, Online Only

Conference Poster

Abstract

Optical diffraction tomography (ODT) as a kind of label-free three-dimensional imaging technique has been widely used in biomedical imaging. To decrease the volume of ODT instrumentation and broaden the applications of the ODT technique, we propose a novel design to achieve a miniaturized ODT system based on using a vertical-cavity surface-emitting laser (VCSEL) array and a self-interference unit. In our proposed system design, a dome-shaped VCSEL array is used to generate angle scanning illuminations, and the self-interference unit is applied to record the off-axis interferograms from different illumination angles. We have verified the accuracy of phase retrieval of our system and investigated the proper illumination angles and reconstruction model for further system development.

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Haojia Sun and Renjie Zhou "Miniaturization of an optical diffraction tomography system", Proc. SPIE 11653, Quantitative Phase Imaging VII, 116531M (5 March 2021); https://doi.org/10.1117/12.2583386

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