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Here we will highlight our recent efforts in translating Raman spectroscopy towards routine clinical applications by developing compact clinically usable automated Raman spectroscopic instrumentation and their combination with other spectroscopic / optical modalities, to provide a multimodal approach with high TRL levels. We will start with novel multimodal spectroscopic instrumentation for precise surgical guidance and intraoperative histopathological examination of tissue and their combination with laser tissue ablation for tissue specific laser surgery and for therapy monitoring. Finally, we report on the application of non-resonant Raman spectroscopy for an early diagnosis of neurodegenerative diseases directly in the fundus of the eye.
Jürgen Popp
"Multicontrast spectroscopy and imaging for translational medicine", Proc. SPIE 11656, Advanced Chemical Microscopy for Life Science and Translational Medicine 2021, 1165607 (5 March 2021); https://doi.org/10.1117/12.2576375
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Jürgen Popp, "Multicontrast spectroscopy and imaging for translational medicine," Proc. SPIE 11656, Advanced Chemical Microscopy for Life Science and Translational Medicine 2021, 1165607 (5 March 2021); https://doi.org/10.1117/12.2576375