Detection of L-Asparagine by surface-enhanced Raman scattering

Karen Hernández Vidales; Javier Méndez; Francisco Javier González

doi:10.1117/12.2577931

5 March 2021 Detection of L-Asparagine by surface-enhanced Raman scattering

Karen Hernández Vidales, Javier Méndez, Francisco Javier González

Proceedings Volume 11657, Biomedical Applications of Light Scattering XI; 116570O (2021) https://doi.org/10.1117/12.2577931
Event: SPIE BiOS, 2021, Online Only

Abstract

In this work, Surface-enhanced Raman Scattering had been applied to detect L-Asparagine. The presence of this amino acid in tissues and fluids helps to the prevalence of acute lymphoblastic leukemia cells and promotes the proliferation of metastasis for some other malignant tumors; depletion of L-Asparagine is up to date the best treatment for leukemia and could improve the prognosis for other cancers. We have carried out the preparation and characterization of two types of metallic surfaces, one with nanoparticles and the other one with nanostructures; we obtained and compared the SERS spectra and enhancement factors between them to emphasize the advantages in each one. The principal aim of this work is to establish the basis for a new reliable biosensor capable of being used in clinical applications.

Conference Presentation

Citation Download Citation

Karen Hernández Vidales, Javier Méndez, and Francisco Javier González "Detection of L-Asparagine by surface-enhanced Raman scattering", Proc. SPIE 11657, Biomedical Applications of Light Scattering XI, 116570O (5 March 2021); https://doi.org/10.1117/12.2577931

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