Literature review on surface and tip enhanced Raman spectroscopy in bioanalytics

Dana Cialla-May

doi:10.1117/12.2595757

7 March 2021 Literature review on surface and tip enhanced Raman spectroscopy in bioanalytics

Dana Cialla-May

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Proceedings Volume 11658, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVIII; 1165804 (2021) https://doi.org/10.1117/12.2595757
Event: SPIE BiOS, 2021, Online Only

Abstract

Powerful detection schemes in bioanalytics are associated with the requirements for molecular specificity, high sensitivity and fast detection times. Surface enhanced Raman spectroscopy (SERS) is known to meet those requirements and the strong capability of this method in bioanalytical detection schemes is due to the enhancement of the molecular specific Raman fingerprint by 6 to 8 orders of magnitude. In order to increase the spatial resolution to the nanometer scale, SERS is combined with scanning probe microscopy creating tip enhanced Raman spectroscopy (TERS). Within this presentation, a literature review on SERS and TERS in bioanalytics is given.

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Dana Cialla-May "Literature review on surface and tip enhanced Raman spectroscopy in bioanalytics", Proc. SPIE 11658, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVIII, 1165804 (7 March 2021); https://doi.org/10.1117/12.2595757

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