CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume 11659 > Article
Presentation
10 March 2021 Remote control of CRISPR nanoplasmonic carriers
Zhijia Zhang, Guangjie Cui, Yunbo Liu, Xintao Zhao, Somin Eunice Lee
Author Affiliations +
Proceedings Volume 11659, Colloidal Nanoparticles for Biomedical Applications XVI; 1165911 (2021) https://doi.org/10.1117/12.2578394
Event: SPIE BiOS, 2021, Online Only
Abstract
CRISPR-Cas9 is an efficient and reliable tool to cleave targeted portions of DNA. Once the DNA been cut by the tool, genes are ready to be cut, inserted or modified as desired. Conventionally, CRISPR is carried by a virus into cells. However, potential safety issues exists, as the cell can physiologically respond to viral invasion, or its genome can be inserted with unwanted virus genes. Here, we show that gold nanoparticles serves as preferable successful vectors of CRISPR-Cas9, with extra benefit to allow stable imaging. This toxicity-free alternative method avoids the aforementioned issues and introduces the CRISPR-Cas9 complex safely
Conference Presentation
© (2021) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Zhijia Zhang, Guangjie Cui, Yunbo Liu, Xintao Zhao, and Somin Eunice Lee "Remote control of CRISPR nanoplasmonic carriers", Proc. SPIE 11659, Colloidal Nanoparticles for Biomedical Applications XVI, 1165911 (10 March 2021); https://doi.org/10.1117/12.2578394
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 PRESENTATION
WATCH
PRESENTATION SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
KEYWORDS
Nanoparticles
Gold
Safety
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top