Wearable sensors have the potential to provide rapid, non-invasive, and in-home health monitoring by real-time analyzing biomarkers in human sweat and saliva. However, most current biosensors suffer from low sensing accuracy for low-level analyte detection in biofluids and are difficult to fabricate on a large scale. In this talk, I will review our latest advances in developing fully-integrated laser-engraved graphene-based biosensors which can selectively and accurately measure a wide spectrum of sweat and saliva biomarkers including metabolites, nutrients, hormones, and proteins. The clinical value of these telemedicine platforms is evaluated through multiple human studies involving both healthy and patient populations toward metabolic monitoring and stress assessment. I will also introduce our recent work on a multiplexed wireless platform for the rapid COVID-19 test which could provide information on infection status, severity, and immunity.
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