Photonic liquid crystals on a single substrate for label-free protein assays

Mon-Juan Lee; Chao-Ping Pai; Po-Chang Wu; Wei Lee

doi:10.1117/12.2593821

1 August 2021 Photonic liquid crystals on a single substrate for label-free protein assays

Mon-Juan Lee, Chao-Ping Pai, Po-Chang Wu, Wei Lee

Author Affiliations +

Proceedings Volume 11807, Liquid Crystals XXV; 1180707 (2021) https://doi.org/10.1117/12.2593821
Event: SPIE Organic Photonics + Electronics, 2021, San Diego, California, United States

Abstract

Label-free qualitative and quantitative protein assays were established with a single-substrate biosensing platform based on cholesteric liquid crystal (CLC) films with different ratios of the thickness d to the helical pitch P. By adjusting the amount of chiral dopant incorporated in CLC, the d/P ratio or the center wavelength of Bragg’s reflection band can be fine-tuned to achieve signal amplification or to improve detection sensitivity. The single-substrate platform eliminates the need for LC cell assembly, which requires a pair of glass substrates, and can be conveniently integrated with the format of most clinical assays performed on a single solid surface.

Conference Presentation

Citation Download Citation

Mon-Juan Lee, Chao-Ping Pai, Po-Chang Wu, and Wei Lee "Photonic liquid crystals on a single substrate for label-free protein assays", Proc. SPIE 11807, Liquid Crystals XXV, 1180707 (1 August 2021); https://doi.org/10.1117/12.2593821

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

;

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE