A method that realizes the three-dimensional holographic laser reconstruction and processing by using an optimized computer-generated hologram (CGH) was demonstrated. A pre-designed CGH that contains three-dimensional (3D) information displayed on a liquid-crystal-on-silicon spatial light modulator (LCOS-SLM) can obtain the desired 3D diffraction pattern in the optical system, called 3D holographic laser reconstruction, and when it is reduced by an objective lens and incident on a sample, it can realize the 3D holographic laser processing. Using an optimization method, called in-system optimization, to compensate for the imperfections that exist in the actual laser system, and obtain the high-quality CGH. Consequently, a high uniformity 3D holographic laser reconstruction was achieved, and the consistent scale of the corresponding processing holes proved the feasibility and significance of the CGH optimization.
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