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Coronary CT Angiography (cCTA) is commonly used to detect and quantify luminal stenoses in patients with coronary artery disease (CAD). However, its use is limited in patients with heavy coronary calcifications due to calcium blooming, which is caused by insufficient spatial resolution. This study evaluated the ability of a photon-counting-detector (PCD) CT in quantifying of luminal stenosis in the presence of heavy calcifications relative to an energy-integrating-detector (EID) CT. The phantom results indicate that with PCD-CT, luminal stenoses that were previously considered non-assessable due to the presence of heavily-calcified plaques can be assessed using cCTA.
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Emily Koons, Patrick D. VanMeter, Kishore Rajendran, Lifeng Yu, Cynthia McCollough, Shuai Leng, "Improved assessment of coronary artery luminal stenosis with heavy calcifications using high-resolution photon-counting detector CT," Proc. SPIE 12031, Medical Imaging 2022: Physics of Medical Imaging, 120311A (4 April 2022); https://doi.org/10.1117/12.2613019