The application of the multimodal approach for studying optical properties of bile in obstructive jaundice

Ksenia Kandurova; Nadezhda Golubova; Vadim Prizemin; Dmitry Sumin; Nikita Adamenkov; Vladimir Shabalin; Andrian Mamoshin; Elena Potapova

doi:10.1117/12.2621289

19 May 2022 The application of the multimodal approach for studying optical properties of bile in obstructive jaundice

Ksenia Kandurova, Nadezhda Golubova, Vadim Prizemin, Dmitry Sumin, Nikita Adamenkov, Vladimir Shabalin, Andrian Mamoshin, Elena Potapova

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Proceedings Volume 12147, Tissue Optics and Photonics II; 121470N (2022) https://doi.org/10.1117/12.2621289
Event: SPIE Photonics Europe, 2022, Strasbourg, France

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Abstract

This article describes the results of experimental studies using optical methods for in vitro estimation of the composition of bile obtained from patients with different etiologies of obstructive jaundice. Experimental studies were carried out using spectrophotometry and Raman spectroscopy methods to study and compare optical properties of bile from patients with obstructive jaundice caused either by choledocholithiasis or malignant tumors. The results show that the selected methods are suitable for studying the composition and optical properties of bile and can provide additional diagnostic information. Averaged Raman spectra, as well as absorption spectra of bile, corresponding to different etiologies of jaundice origin were demonstrated.

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Ksenia Kandurova, Nadezhda Golubova, Vadim Prizemin, Dmitry Sumin, Nikita Adamenkov, Vladimir Shabalin, Andrian Mamoshin, and Elena Potapova "The application of the multimodal approach for studying optical properties of bile in obstructive jaundice", Proc. SPIE 12147, Tissue Optics and Photonics II, 121470N (19 May 2022); https://doi.org/10.1117/12.2621289

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