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1 July 1990 Tabletop CT system for high-resolution volume imaging
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Abstract
We have constructed a table-top CT system with high spatial resolution in all three dimensions which can be used to analyze excised tissue samples in vitro. Our system uses an x-ray image intensifier, optically coupled to a time delay integration (ThI) CCD to obtain low-noise, low-scatter projection radiographs of the sample volume. Rather than collecting one projection line at a time (as in conventional CT scanners), the architecture of the TDI-CCD allows us to collect 96 image lines simultaneously. The digital radiograph is formed by scanning a slot-beam of radiation across the sample, reducing the detection of scattered radiation without excessive x-ray tube heat loading. Objects to be imaged are placed on a computer-controlled stage and projections are obtained as the sample is rotated. A water bath surrounds the sample to equalize the exposure to the image intensifier, thereby reducing the dynamic range of the input signal. CT reconstruction of this data results in a 512 volume image with 0.13 x 0.13 mm pixels in the transverse plane and a slice thickness of 0.15 mm. This table-top CTscanner has been used to investigate the properties of intact, excised human arterial samples as part of our research into the development of vascular disease.
© (1990) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
David W. Holdsworth, Maria Drangova, Klaus S. Schulenburg, and Aaron Fenster "Tabletop CT system for high-resolution volume imaging", Proc. SPIE 1231, Medical Imaging IV: Image Formation, (1 July 1990); https://doi.org/10.1117/12.18801
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