Reproducibility of T1ρ MRI in the healthy human knee joint by measuring intra- and inter-vendor variability

Ryan Armbruster; Anjali Talluru; Arijitt Borthakur; Warren Bilker; Ravinder Reddy; Susanta Sarkar

doi:10.1117/12.2653942

10 April 2023 Reproducibility of T1ρ MRI in the healthy human knee joint by measuring intra- and inter-vendor variability

Ryan Armbruster, Anjali Talluru, Arijitt Borthakur, Warren Bilker, Ravinder Reddy, Susanta Sarkar

Author Affiliations +

Proceedings Volume 12468, Medical Imaging 2023: Biomedical Applications in Molecular, Structural, and Functional Imaging; 124680C (2023) https://doi.org/10.1117/12.2653942
Event: SPIE Medical Imaging, 2023, San Diego, California, United States

Abstract

Our work is a first step towards clinically validating 3D T1ρ MRI to be used for routine clinical diagnosis of Osteoarthritis (OA) and for measuring the progression of the disease and its response to therapy in OA clinical trials. Reproducibility of T1ρ values(ms) were first measured using a phantom and then on heathy participants using both Siemens 3T Prisma and GE 3T Architect clinical scanners. Intra- and inter-vendor variability was assessed on each patient and scanner with 3 test-retest scans.

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Citation Download Citation

Ryan Armbruster, Anjali Talluru, Arijitt Borthakur, Warren Bilker, Ravinder Reddy, and Susanta Sarkar "Reproducibility of T1ρ MRI in the healthy human knee joint by measuring intra- and inter-vendor variability", Proc. SPIE 12468, Medical Imaging 2023: Biomedical Applications in Molecular, Structural, and Functional Imaging, 124680C (10 April 2023); https://doi.org/10.1117/12.2653942

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KEYWORDS

Magnetic resonance imaging

Cartilage

Scanners

Clinical trials

Injuries

In vivo imaging

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