Graphene integrated optical biosensor for detection of breast cancer cell media

Jiaxing Sun; Hanlin Jiang; Amanda S. Coutts; Weidong Zhu; John Hunt; Xianfeng Chen

doi:10.1117/12.3000582

12 March 2024 Graphene integrated optical biosensor for detection of breast cancer cell media

Jiaxing Sun, Hanlin Jiang, Amanda S. Coutts, Weidong Zhu, John Hunt, Xianfeng Chen

Proceedings Volume 12835, Optical Fibers and Sensors for Medical Diagnostics, Treatment, and Environmental Applications XXIV; 1283502 (2024) https://doi.org/10.1117/12.3000582
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

We report a graphene oxide integrated optical biosensor for the detection of breast cancer cell media. The graphene oxide nanosheets-coated long period grating (GO-LPG) serves as an optical transducer where the GO acts as a bridging interface between optical sensor and external medium. The principle of the optical biosensor is based on alerting the optical signal as a change of local refractive index caused by different analyte concentrations. The proposed biosensor has been implemented to detect the breast cancer cell media with ultrahigh sensitivity, opening the path as a bio-nano-photonic platform for biosensing and early diagnosis.

Conference Presentation

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Jiaxing Sun, Hanlin Jiang, Amanda S. Coutts, Weidong Zhu, John Hunt, and Xianfeng Chen "Graphene integrated optical biosensor for detection of breast cancer cell media", Proc. SPIE 12835, Optical Fibers and Sensors for Medical Diagnostics, Treatment, and Environmental Applications XXIV, 1283502 (12 March 2024); https://doi.org/10.1117/12.3000582

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