Design considerations of a real-time clinical confocal microscope

Barry R. Masters

doi:10.1117/12.43957

1 June 1991 Design considerations of a real-time clinical confocal microscope

Barry R. Masters

Proceedings Volume 1423, Ophthalmic Technologies; (1991) https://doi.org/10.1117/12.43957
Event: Optics, Electro-Optics, and Laser Applications in Science and Engineering, 1991, Los Angeles, CA, United States

Abstract

A real-time clinical confocal light microscope provides the ophthalmologist with a new tool for the observation of the cornea and the ocular lens. In addition, the ciliary body, the iris, and the sclera can be observed. The real-time light microscopic images have high contrast and resolution. The transverse resolution is about one half micron and the range resolution is one micron. The following observations were made with visible light: corneal epithelial cells, wing cells, basal cells, Bowman's membrane, nerve fibers, basal lamina, fibroblast nuclei, Descemet's membrane, endothelial cells. Observation of the in situ ocular lens showed lens capsule, lens epithelium, lens fibrils, the interior of lens fibrils. The applications of the confocal microscope include: eye banking, laser refractive surgery, observation of wound healing, observation of the iris, the sciera, the ciliary body, the ocular lens, and the intraocular lens. Digital image processing can produce three-dimensional reconstructions of the cornea and the ocular lens.

Citation Download Citation

Barry R. Masters "Design considerations of a real-time clinical confocal microscope", Proc. SPIE 1423, Ophthalmic Technologies, (1 June 1991); https://doi.org/10.1117/12.43957

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