Near-infrared optical monitoring of cardiac oxygen sufficiency through thoracic wall without open-chest surgery

Yasuyuki Kakihana M.D.; Mamoru Tamura

doi:10.1117/12.44202

1 May 1991 Near-infrared optical monitoring of cardiac oxygen sufficiency through thoracic wall without open-chest surgery

Yasuyuki Kakihana M.D., Mamoru Tamura

Author Affiliations +

Proceedings Volume 1431, Time-Resolved Spectroscopy and Imaging of Tissues; (1991) https://doi.org/10.1117/12.44202
Event: Optics, Electro-Optics, and Laser Applications in Science and Engineering, 1991, Los Angeles, CA, United States

Abstract

The cardiac function is exquisitely sensitive to oxygen, because its energy production mainly depends on the oxidative phosphorylation at mitochondria. Thus, oxygenation state of the tissue is critical. Cytochrome a,a3, hemoglobin and myoglobin, which play indispensable role in the oxygen metabolism, have the broad absorption band in near infrared (NIR) region and the light in this region easily penetrates biological tissues. Using NIR spectrophotometry, we attempted to measure the redox state of the copper in cytochrome a,a3 in rat heart through thoracic wall without open chest. The result is given in this paper.

Citation Download Citation

Yasuyuki Kakihana M.D. and Mamoru Tamura "Near-infrared optical monitoring of cardiac oxygen sufficiency through thoracic wall without open-chest surgery", Proc. SPIE 1431, Time-Resolved Spectroscopy and Imaging of Tissues, (1 May 1991); https://doi.org/10.1117/12.44202

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