Time-resolved diffuse reflectance and transmittance studies in tissue simulating phantoms: a comparison between theory and experiment

Sten Madsen; Michael S. Patterson; Brian C. Wilson; Young D. Park; John David Moulton; Steven L. Jacques; Yaron Hefetz

doi:10.1117/12.44176

1 May 1991 Time-resolved diffuse reflectance and transmittance studies in tissue simulating phantoms: a comparison between theory and experiment

Sten Madsen, Michael S. Patterson, Brian C. Wilson, Young D. Park, John David Moulton, Steven L. Jacques, Yaron Hefetz

Author Affiliations +

Proceedings Volume 1431, Time-Resolved Spectroscopy and Imaging of Tissues; (1991) https://doi.org/10.1117/12.44176
Event: Optics, Electro-Optics, and Laser Applications in Science and Engineering, 1991, Los Angeles, CA, United States

Abstract

When a picosecond light pulse is incident on an optically turbid medium such as tissue, the temporal distribution of diffusely reflected and transmitted photons depends on the optical absorption and scattering properties of the medium. From diffusion theory it is possible to derive analytic expressions for the pulse shape in terms of the optical interaction coefficients of a homogeneous semi-infinite medium. Experimental tests of this model in tissue-simulating liquid phantoms of different geometries are presented here.

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Sten Madsen, Michael S. Patterson, Brian C. Wilson, Young D. Park, John David Moulton, Steven L. Jacques, and Yaron Hefetz "Time-resolved diffuse reflectance and transmittance studies in tissue simulating phantoms: a comparison between theory and experiment", Proc. SPIE 1431, Time-Resolved Spectroscopy and Imaging of Tissues, (1 May 1991); https://doi.org/10.1117/12.44176

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