Imaging of excimer laser vascular tissue ablation by ultrafast photography

Ralf Nyga; Walter Neu; M. Preisack; Karl Konstantin Haase M.D.; Karl R. Karsch M.D.

doi:10.1117/12.48211

1 November 1991 Imaging of excimer laser vascular tissue ablation by ultrafast photography

Ralf Nyga, Walter Neu, M. Preisack, Karl Konstantin Haase M.D., Karl R. Karsch M.D.

Proceedings Volume 1525, Future Trends in Biomedical Applications of Lasers; (1991) https://doi.org/10.1117/12.48211
Event: MedTech '91, 1991, Berlin, Germany

Abstract

Ablation and tissue removal of normal and atherosclerotic arterial tissue by UV excimer-laser radiation were probed by taking photographs with a dye laser as a flash light-source. The ablating pulses were transmitted through a fused silica fiber into a cuvette with the samples exposed to saline solution. The delay time of the probing dye-laser pulse with respect to the ablating excimer-laser pulse was varied in the nanosecond range up to several hundred microseconds. The ablation process and the resulting plume above the tissue surface were recorded with a CCD camera attached to a PC-based image processing system. All samples under investigation were fresh human cadaver aortic and femoral artery specimens which had been shock-frozen for less than 48 hours. The arterial segments showed different types of lipid-rich and calcified plaques. Big cavitation bubbles and small tissue particles emerging from the irradiated area have been recorded.

Citation Download Citation

Ralf Nyga, Walter Neu, M. Preisack, Karl Konstantin Haase M.D., and Karl R. Karsch M.D. "Imaging of excimer laser vascular tissue ablation by ultrafast photography", Proc. SPIE 1525, Future Trends in Biomedical Applications of Lasers, (1 November 1991); https://doi.org/10.1117/12.48211

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