Three-year experience in the application of PDT in the treatment of lung cancer

D. Kostadinov; Emil Benov; K. Mitchev; V. Vlasov; Giulio Jori

doi:10.1117/12.136956

5 March 1993 Three-year experience in the application of PDT in the treatment of lung cancer

D. Kostadinov, Emil Benov, K. Mitchev, V. Vlasov, Giulio Jori

Proceedings Volume 1616, International Conference on Photodynamic Therapy and Laser Medicine; (1993) https://doi.org/10.1117/12.136956
Event: International Conference on Photodynamic Therapy and Laser Medicine, 1991, Beijing, China

Abstract

During a 3 year period, 20 patients with morphologically proven squamous cell carcinoma of the trachea or bronchi have been treated by photoradiation therapy (PRT). A Bulgarian gold vapor laser and hematoporphyrin of `Jacopo Monico,' Italy were used. The photosensitizer was applied intravenously 24 - 48 h prior to PDT. The median realized energy dose was 410 J/cm² for each patient with a middle power of 180 mW. In 5 of all the cases we performed two sessions. The obtained therapeutic results are as follows: CR -- one case (5%), SR -- 10 cases (50%), NR -- 3 cases (15%). The median survival of the patients with advanced cancer was 13.3 months. At the end of 1990 three patients were alive. Our experience shows that PRT is a promising palliative method in cases of advanced carcinoma for the recanalization of airways.

Citation Download Citation

D. Kostadinov, Emil Benov, K. Mitchev, V. Vlasov, and Giulio Jori "Three-year experience in the application of PDT in the treatment of lung cancer", Proc. SPIE 1616, International Conference on Photodynamic Therapy and Laser Medicine, (5 March 1993); https://doi.org/10.1117/12.136956

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