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28 August 1992 Excimer laser angioplasty in conjunction with intravascular ultrasonic imaging
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The use of the excimer laser for ablation of atherosclerotic plaque in the coronary and peripheral vasculature has been evaluated extensively in recent years. (Approximately 3,800 patients treated worldwide.) It may be possible to utilize an ultrasound image as a guide during the excimer laser procedure to determine whether additional plaque extraction should be performed. Also, as excimer laser catheters become more lesion specific and steerable it is imperative that the interventionalist is provided with a method to judge lesions other than by the `blind' guidance provided with contrast angiography. Intravascular ultrasound is a technology which could provide guidance to differentiate between normal and stenotic wall in high-grade eccentric lesions. For real-time monitoring with the excimer/ultrasound combination, we utilized a 2.2 mm peripheral excimer laser angioplasty catheter (Spectranetics Corporation) incorporating a 2.5 French intravascular ultrasound transducer within the central guidewire lumen (Boston Scientific Corporation). In this paper, we discuss our preliminary in- vivo experiments designed to illustrate ultrasound-guided excimer laser angioplasty and monitor laser ablation in stenotic porcine iliac arteries.
© (1992) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Daniel J. Kasprzyk, Jeffrey M. Isner M.D., and Robert J. Crowley "Excimer laser angioplasty in conjunction with intravascular ultrasonic imaging", Proc. SPIE 1642, Diagnostic and Therapeutic Cardiovascular Interventions II, (28 August 1992);

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