Wound healing enhancement of colonic anastomoses after endoscopic irradiation with low-power He-Ne laser: an experimental study after mechanical obstruction

Francisco Asencio-Arana M.D.; Vicente Garcia-Fons M.D.; E. Moloina-Andreu

doi:10.1117/12.137344

1 June 1992 Wound healing enhancement of colonic anastomoses after endoscopic irradiation with low-power He-Ne laser: an experimental study after mechanical obstruction

Francisco Asencio-Arana M.D., Vicente Garcia-Fons M.D., E. Moloina-Andreu

Author Affiliations +

Proceedings Volume 1643, Laser Surgery: Advanced Characterization, Therapeutics, and Systems III; (1992) https://doi.org/10.1117/12.137344
Event: OE/LASE '92, 1992, Los Angeles, CA, United States

Abstract

We have tested the strength and collagen concentration of high-risk anastomoses of the rat colon after endoscopic irradiation by He-Ne laser. Repeated He-Ne laser irradiation (1.9 J/cm²) increases the bursting strength of the anastomoses by almost 100% on the fourth postoperative day. This effect is not observed by increasing the radiation dose (6.4 J/cm²). Differences in collagen (hydroxyproline) concentration did not reach statistical significance. Our study suggests that repeated endoscopic irradiation with He-Ne laser enhances the early phases of anastomotic healing in high risk colonic anastomoses.

Citation Download Citation

Francisco Asencio-Arana M.D., Vicente Garcia-Fons M.D., and E. Moloina-Andreu "Wound healing enhancement of colonic anastomoses after endoscopic irradiation with low-power He-Ne laser: an experimental study after mechanical obstruction", Proc. SPIE 1643, Laser Surgery: Advanced Characterization, Therapeutics, and Systems III, (1 June 1992); https://doi.org/10.1117/12.137344

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