CO laser angioplasty system: efficacy of manipulatable laser angioscope catheter

Tsunenori Arai; Makoto Kikuchi; Kyoichi Mizuno; Masami Sakurada; Akira Miyamoto M.D.; Koh Arakawa; Akira Kurita; Haruo Nakamura M.D.; Kiyoshi Takeuchi; Atsushi Utsumi; Yoshiro Akai

doi:10.1117/12.60224

1 August 1992 CO laser angioplasty system: efficacy of manipulatable laser angioscope catheter

Tsunenori Arai, Makoto Kikuchi, Kyoichi Mizuno, Masami Sakurada, Akira Miyamoto M.D., Koh Arakawa, Akira Kurita, Haruo Nakamura M.D., Kiyoshi Takeuchi, Atsushi Utsumi, Yoshiro Akai

Author Affiliations +

Proceedings Volume 1649, Optical Fibers in Medicine VII; (1992) https://doi.org/10.1117/12.60224
Event: OE/LASE '92, 1992, Los Angeles, CA, United States

Abstract

A percutaneous transluminal coronary angioplasty system using a unique combination of CO laser (5 micrometers ) and As-S infrared glass fiber under the guidance of a manipulatable laser angioscope catheter is described. The ablation and guidance functions of this system are evaluated. The angioplasty treatment procedure under angioscope guidance was studied by in vitro model experiment and in vivo animal experiment. The whole angioplasty system is newly developed. That is, a transportable compact medical CO laser device which can emit up to 10 W, a 5 F manipulatable laser angioscope catheter, a thin CO laser cable of which the diameter is 0.6 mm, an angioscope imaging system for laser ablation guidance, and a system controller were developed. Anesthetized adult mongrel dogs (n equals 5) with an artificial complete occlusion in the femoral artery and an artificial human vessel model including occluded or stenotic coronary artery were used. The manipulatability of the catheter was drastically improved (both rotation and bending), therefore, precise control of ablation to expand stenosis was obtained. A 90% artificial stenosis made of human yellow plaque in 4.0 mm diameter in the vessel was expanded to 70% stenosis by repetitive CO laser ablations of which total energy was 220 J. All procedures were performed and controlled under angioscope visualization.

Citation Download Citation

Tsunenori Arai, Makoto Kikuchi, Kyoichi Mizuno, Masami Sakurada, Akira Miyamoto M.D., Koh Arakawa, Akira Kurita, Haruo Nakamura M.D., Kiyoshi Takeuchi, Atsushi Utsumi, and Yoshiro Akai "CO laser angioplasty system: efficacy of manipulatable laser angioscope catheter", Proc. SPIE 1649, Optical Fibers in Medicine VII, (1 August 1992); https://doi.org/10.1117/12.60224

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