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Film subtraction angiography from intravenous injections of iodinated contrast media was one of the earliest radiographic methods used to visualize the heart and blood vessels. Initially used for studies to visualize the cardiac chambers and the aorta, this technique has been supplanted by the more sophisticated (and invasive) methods of selective catheter angiography because of the superior images obtained by virtue of higher intravascular iodine concentrations.
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William R. Brody, "Intravenous Contrast Angiography," Proc. SPIE 0167, Noninvasive Cardiovascular Measurements, (19 June 1979); https://doi.org/10.1117/12.956980