Vapor bubble expansion and implosion: the origin of "Mille Feuilles"

Ton G. J. M. van Leeuwen; Lieselotte van Erven; John H. Meertens; Mark J. Post; Cornelius Borst M.D.

doi:10.1117/12.146581

23 June 1993 Vapor bubble expansion and implosion: the origin of "Mille Feuilles"

Ton G. J. M. van Leeuwen, Lieselotte van Erven, John H. Meertens, Mark J. Post, Cornelius Borst M.D.

Proceedings Volume 1878, Diagnostic and Therapeutic Cardiovascular Interventions III; (1993) https://doi.org/10.1117/12.146581
Event: OE/LASE'93: Optics, Electro-Optics, and Laser Applications in Scienceand Engineering, 1993, Los Angeles, CA, United States

Abstract

The aim of our study was to demonstrate, in vivo, bubble expansion in blood and to assess any damage to the arterial wall after 1 - 10 excimer laser pulses (55 mJ/mm²). Time resolved flash photography demonstrated the expansion and implosion of a vapor bubble, which induced a 50% diameter increase of the artery within 75 microsecond(s) and a subsequent invagination (150 - 500 microsecond(s) ). This microsecond dilation and invagination caused extensive wall damage (up to 1.9 mm) far beyond the penetration depth of 308 nm laser light (< 100 micrometers ). The damage, which increased with the number of laser pulses, may be related to the dissections observed after excimer laser coronary angioplasty.

Citation Download Citation

Ton G. J. M. van Leeuwen, Lieselotte van Erven, John H. Meertens, Mark J. Post, and Cornelius Borst M.D. "Vapor bubble expansion and implosion: the origin of "Mille Feuilles"", Proc. SPIE 1878, Diagnostic and Therapeutic Cardiovascular Interventions III, (23 June 1993); https://doi.org/10.1117/12.146581

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