Measurement of physiological flow parameters with magnetic resonance

Charles L. Dumoulin; M. Tarnawski; D. J. Doorly; C. G. Caro; R. D. Darrow

doi:10.1117/12.151198

27 August 1993 Measurement of physiological flow parameters with magnetic resonance

Charles L. Dumoulin, M. Tarnawski, D. J. Doorly, C. G. Caro, R. D. Darrow

Proceedings Volume 1887, Physiological Imaging, Spectroscopy, and Early-Detection Diagnostic Methods; (1993) https://doi.org/10.1117/12.151198
Event: OE/LASE'93: Optics, Electro-Optics, and Laser Applications in Scienceand Engineering, 1993, Los Angeles, CA, United States

Abstract

Some phase-sensitive methods obtain a phase measurement for each voxel in an otherwise conventional image. In an alternative approach, data for a variety of flow-sensitive conditions are obtained and Fourier transformed to obtain a velocity 'spectrum'. Fourier velocity encoded data are highly accurate and are not degraded by velocity distributions within a voxel. One important application of Fourier velocity encoding is the non-invasive measurement of local vessel wall compliance. We have developed a new technique in which spin velocity information is acquired simultaneously for several stations along a vessel using a comb excitation rf pulse and Fourier velocity encoding. In the absence of pulse wave reflections, two stations separated by a sufficient distance are enough to calculate the velocity of the pressure wave, C. Once the wave velocity is known, it can be used to determine vessel wall distensibility, D, using the relationship D equals 1/((rho) C²), where (rho) is the density of blood. Preliminary data from a group of healthy volunteers suggest a strong correlation of local vessel compliance with physical fitness and age.

Citation Download Citation

Charles L. Dumoulin, M. Tarnawski, D. J. Doorly, C. G. Caro, and R. D. Darrow "Measurement of physiological flow parameters with magnetic resonance", Proc. SPIE 1887, Physiological Imaging, Spectroscopy, and Early-Detection Diagnostic Methods, (27 August 1993); https://doi.org/10.1117/12.151198

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