Monitoring of fermentation parameters with fiber optics

Venetka I. Agayn; David R. Walt

doi:10.1117/12.170688

10 March 1994 Monitoring of fermentation parameters with fiber optics

Venetka I. Agayn, David R. Walt

Proceedings Volume 2068, Chemical, Biochemical, and Environmental Fiber Sensors V; (1994) https://doi.org/10.1117/12.170688
Event: Optical Tools for Manufacturing and Advanced Automation, 1993, Boston, MA, United States

Abstract

Bioprocess control requires reliable and continuous monitoring of nutrients and various process parameters, such as dissolved oxygen, carbon dioxide, and pH. Currently, the on-line control of these parameters is achieved electrochemically via dip-in electrodes or indirectly by off-gas analysis. Optical sensors offer an alternative to these conventional methods. Fiber- optic sensors for measuring pH, CO₂ and O₂ have been developed. We have demonstrated the use of a fiber-optic sensor for the continuous monitoring of fermentation pH. In this paper we discuss the use of a ratiometric method and medium calibration as a way to improve the precision of the fiber-optic sensor.

Citation Download Citation

Venetka I. Agayn and David R. Walt "Monitoring of fermentation parameters with fiber optics", Proc. SPIE 2068, Chemical, Biochemical, and Environmental Fiber Sensors V, (10 March 1994); https://doi.org/10.1117/12.170688

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