Photodynamic therapy photosensitizers derived from chlorophyll a

Raymond Bonnett; Robin Benzie; Michael F. Grahn; A. Salgado; Maria Asuncion Valles

doi:10.1117/12.168650

1 March 1994 Photodynamic therapy photosensitizers derived from chlorophyll a

Raymond Bonnett, Robin Benzie, Michael F. Grahn, A. Salgado, Maria Asuncion Valles

Proceedings Volume 2078, Photodynamic Therapy of Cancer; (1994) https://doi.org/10.1117/12.168650
Event: Europto Biomedical Optics '93, 1993, Budapest, Hungary

Abstract

A series of hydroxychlorins and another of (omega) -carboxyalkyloxy derivatives have been prepared from chlorophyll (alpha) , and their potential photosensitizing ability for the photodynamic therapy of cancer tested in vitro by the MTT assay. The results show that the monohydroxychlorin VI, because of its high photoactivity and its low dark toxicity, is the most promising compound of these series.

Citation Download Citation

Raymond Bonnett, Robin Benzie, Michael F. Grahn, A. Salgado, and Maria Asuncion Valles "Photodynamic therapy photosensitizers derived from chlorophyll a", Proc. SPIE 2078, Photodynamic Therapy of Cancer, (1 March 1994); https://doi.org/10.1117/12.168650

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available