Photodynamic therapy of cancer with the photosensitizer PHOTOGEM

Victor V. Sokolov; Valery I. Chissov; E. V. Filonenko; Garry M. Sukhin; Raisa I. Yakubovskaya; T. A. Belous; Natalia N. Zharkova; Dmitrij N. Kozlov; V. V. Smirnov

doi:10.1117/12.199169

12 January 1995 Photodynamic therapy of cancer with the photosensitizer PHOTOGEM

Victor V. Sokolov, Valery I. Chissov, E. V. Filonenko, Garry M. Sukhin, Raisa I. Yakubovskaya, T. A. Belous, Natalia N. Zharkova, Dmitrij N. Kozlov, V. V. Smirnov

Author Affiliations +

Proceedings Volume 2325, Photodynamic Therapy of Cancer II; (1995) https://doi.org/10.1117/12.199169
Event: International Symposium on Biomedical Optics Europe '94, 1994, Lille, France

Abstract

The first clinical trials of photodynamic therapy (PDT) in Russia were started in P. A. Hertzen Moscow Research Oncology Institute in October of 1992. Up to now, 61 patients with primary or recurrent malignant tumors of the larynx (3), trachea (1), bronchus (11), nose (1), mouth (3), esophagus (12), vagina and uterine cervix (3), bladder (2), skin (6), and cutaneous and subcutaneous metastases of breast cancer and melanomas (6) have been treated by PDT with the photosensitizer Photogem. At least partial tumor response was observed in all of the cases, but complete remission indicating no evident tumors has been reached in 51% of the cases. Among 29 patients with early and first stage cancer 14 patients had multifocal tumors. Complete remission of tumors in this group reached 86%.

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Victor V. Sokolov, Valery I. Chissov, E. V. Filonenko, Garry M. Sukhin, Raisa I. Yakubovskaya, T. A. Belous, Natalia N. Zharkova, Dmitrij N. Kozlov, and V. V. Smirnov "Photodynamic therapy of cancer with the photosensitizer PHOTOGEM", Proc. SPIE 2325, Photodynamic Therapy of Cancer II, (12 January 1995); https://doi.org/10.1117/12.199169

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