Resonance Raman studies of hydrogen-bonded solutions: quantitative comparisons of experiment with ab initio calculations

Bruce S. Hudson

doi:10.1117/12.197435

2 January 1995 Resonance Raman studies of hydrogen-bonded solutions: quantitative comparisons of experiment with ab initio calculations

Bruce S. Hudson

Author Affiliations +

Proceedings Volume 2370, 5th International Conference on Laser Applications in Life Sciences; (1995) https://doi.org/10.1117/12.197435
Event: Laser Applications in Life Sciences: 5th International Conference, 1994, Minsk, Belarus

Abstract

Resonance Raman studies of simple peptides have provided a new view of the electronic excitations of these important chromophores. The large effect of isotropic substitution and of hydrogen bonding on resonance Raman spectra provide a new method for testing theoretical calculations. These calculations can be refined by direct comparison of theory with experiment and also used to evaluate the likelihood that further experiments will provide interesting new information. Our recent work has shown how fruitful this cyclic interaction can be. In this on going exploration we are developing experimental methods and testing theoretical descriptions of the electronic excitations of peptides and related ultraviolet chromophores of proteins in solution. The specific areas of interest are (1) examination of the effect of hydrogen bonding on the electronic excitation of peptides; (2) evaluation of the effects of fluctuations in solvation on the electronic excitations of peptides; and (3) studies of the n(pi) * and higher energy electronic excitations of peptides predicted by theory and potentially important in the description of circular dichroism.

Citation Download Citation

Bruce S. Hudson "Resonance Raman studies of hydrogen-bonded solutions: quantitative comparisons of experiment with ab initio calculations", Proc. SPIE 2370, 5th International Conference on Laser Applications in Life Sciences, (2 January 1995); https://doi.org/10.1117/12.197435

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available