Spectroscopy analysis of tissues in vivo

Victor B. Loschenov; P. V. Poleshkin; Alexander A. Stratonnikov; Nadezgda L. Torshina

doi:10.1117/12.197481

2 January 1995 Spectroscopy analysis of tissues in vivo

Victor B. Loschenov, P. V. Poleshkin, Alexander A. Stratonnikov, Nadezgda L. Torshina

Proceedings Volume 2370, 5th International Conference on Laser Applications in Life Sciences; (1995) https://doi.org/10.1117/12.197481
Event: Laser Applications in Life Sciences: 5th International Conference, 1994, Minsk, Belarus

Abstract

The spectral analysis of biological tissues in vivo is widely used in various fields particularly in medical diagnostics and therapy control. Great possibilities of spectral tissue analysis exist to be realized in the future. Among them are the complete non-invasive clinical blood analysis with evaluation of, for example, sugar concentration in blood; the evaluation of chemical state and localization on subcell level of various drugs binded with biological structures. These facts were shown to affect drastically the drug therapeutic activity. The main advantage of spectral analysis of tissues in vivo is its noninvasivity. This allows one to get information about tissue condition without affecting the dynamic of various biological processes. Another advantage of optical tissue analysis is the possibility to process data in real time and to control parameters of therapy process according to information acquired. For example the in situ analysis of photosensitizer concentration and its chemical state during photodynamic therapy makes it possible to correct the laser irradiation intensity (the photobleaching of photosensitizer requires the decrease in laser intensity).

Citation Download Citation

Victor B. Loschenov, P. V. Poleshkin, Alexander A. Stratonnikov, and Nadezgda L. Torshina "Spectroscopy analysis of tissues in vivo", Proc. SPIE 2370, 5th International Conference on Laser Applications in Life Sciences, (2 January 1995); https://doi.org/10.1117/12.197481

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