Near-infrared monitoring of hemoglobin content in the kidney during ischemia

Wendy J. Snyder; Jean-Michel I. Maarek; Sandor G. Vari M.D.; Laura Marcu; Thanassis Papaioannou; Vani R. Pergadia; Warren S. Grundfest M.D.

doi:10.1117/12.206827

12 April 1995 Near-infrared monitoring of hemoglobin content in the kidney during ischemia

Wendy J. Snyder, Jean-Michel I. Maarek, Sandor G. Vari M.D., Laura Marcu, Thanassis Papaioannou, Vani R. Pergadia, Warren S. Grundfest M.D.

Author Affiliations +

Proceedings Volume 2387, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases II; (1995) https://doi.org/10.1117/12.206827
Event: Photonics West '95, 1995, San Jose, CA, United States

Abstract

Near infrared spectroscopy was used to monitor changes in hemoglobin concentration in the kidney of 9 anesthetized rabbits during ischemic conditions. Laser diodes (775, 810, 862, and 904 nm) were placed on the surface of the kidney, the transmitted light was detected by a photomultiplier. Three stages of ischemia were induced in the kidney by occluding the abdominal aorta to approximately 1/3, 2/3 and total occlusion. Hemoglobin content was monitored during 10 minutes of occlusion followed by 10 minutes of recovery. The occlusions resulted in an average decrease in blood pressure of 36%, 53% and 100% in the abdominal aorta. The partial occlusions resulted in an increasing trend in total hemoglobin content during the 10 minutes occlusion followed by a return to baseline hemoglobin concentration. Within the first 30 seconds of the total occlusion maneuver, an immediate decrease in hemoglobin content was observed. During the occlusion the hemoglobin content increases slowly, corresponding to an increase in reduced hemoglobin content. Oxygenated hemoglobin content remained constant during the occlusion and increased immediately when the occlusion was released.

Citation Download Citation

Wendy J. Snyder, Jean-Michel I. Maarek, Sandor G. Vari M.D., Laura Marcu, Thanassis Papaioannou, Vani R. Pergadia, and Warren S. Grundfest M.D. "Near-infrared monitoring of hemoglobin content in the kidney during ischemia", Proc. SPIE 2387, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases II, (12 April 1995); https://doi.org/10.1117/12.206827

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
7 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Kidney

Blood

Ischemia

Blood circulation

Near infrared spectroscopy

Blood pressure

Semiconductor lasers

Show All Keywords

Keywords/Phrases

Search In:

Publication Years