Random walk analysis of the effects of the presence of abnormalities in a turbid medium on expressions for the time-of-flight

Amir H. Gandjbakhche; George H. Weiss

doi:10.1117/12.206810

12 April 1995 Random walk analysis of the effects of the presence of abnormalities in a turbid medium on expressions for the time-of-flight

Amir H. Gandjbakhche, George H. Weiss

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Proceedings Volume 2387, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases II; (1995) https://doi.org/10.1117/12.206810
Event: Photonics West '95, 1995, San Jose, CA, United States

Abstract

Time-gated transillumination techniques for detecting and resolving regions of abnormal absorption and/or scattering in a slab geometry are based on the ability to detect transmitted photons that are nearly ballistic, i.e., that arrive at relatively short times after initial injection at a detector. However, at short gating times, the detectable intensity quickly falls below a practical detection threshold with increasing slab thickness. A quantitative theory of this effect is easily developed within the framework of random walk theory. Such a theoretical development has been shown to yield quite good approximations for properties of photon transport in a homogeneous multiply-scattering medium. Mathematical solutions of the random walk model are used to suggest experimentally measurable parameters with potential applicability tot he detection of abnormalities when their optical coefficients differ form those of the background.

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Amir H. Gandjbakhche and George H. Weiss "Random walk analysis of the effects of the presence of abnormalities in a turbid medium on expressions for the time-of-flight", Proc. SPIE 2387, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases II, (12 April 1995); https://doi.org/10.1117/12.206810

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KEYWORDS

Photons

Scattering

Tissues

Absorption

Photon transport

Sensors

Tissue optics

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