Controlled temperature tissue fusion: Ho:YAG laser welding of rat intestine in vivo

Inci F. Cilesiz; Eric K. Chan; Ashley J. Welch; Sharon L. Thomsen M.D.

doi:10.1117/12.209141

12 May 1995 Controlled temperature tissue fusion: Ho:YAG laser welding of rat intestine in vivo

Inci F. Cilesiz, Eric K. Chan, Ashley J. Welch, Sharon L. Thomsen M.D.

Proceedings Volume 2395, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems V; (1995) https://doi.org/10.1117/12.209141
Event: Photonics West '95, 1995, San Jose, CA, United States

Abstract

The results of a closed loop thermal feedback controlled laser-assisted tissue welding study in vivo are reported. A series of experiments was carried out to study and compare the weld strength and healing response of sutured and laser welded rat enterotomies with and without temperature feedback control (TFC) using a cryogenically cooled Ho:YAG laser. Although assignment of animals to three groups (control sutured, laser welded with and without TFC) and four observation periods (1, 3, 7, and 21 days) was randomized, several laser welded enterotomies without TFC had complications resulting in death of the animals. Those experiments were repeated. From the failure rates encountered, it is shown that TFC improves the quality of laser-assisted enterotomy closures.

Citation Download Citation

Inci F. Cilesiz, Eric K. Chan, Ashley J. Welch, and Sharon L. Thomsen M.D. "Controlled temperature tissue fusion: Ho:YAG laser welding of rat intestine in vivo", Proc. SPIE 2395, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems V, (12 May 1995); https://doi.org/10.1117/12.209141

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