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9 October 1995Near-infrared fluorescence sensor technology
Fluorescence spectroscopy has been used extensively to solve environmental problems (including biological, water quality, separation and etc.). Despite its numerous applications, long wavelength, near- infrared (NIR) fluorescence has been the subject of very few studies. This wavelength region is advantageous, if we wish to minimize the effect of background interference. Lowering the background interference is especially advantageous in environmental monitoring applications where very little or no preseparation is necessary to achieve selective measurements. The applications of NIR absorbing fluorophores which usually have high molar absorptivities and good quantum yields can be especially advantageous when laser diodes are employed as the excitation source. This paper will focus on several general practical analytical applications of NIR fluorescence spectroscopy for solving environmental related analytical problems, including but not limited to: use of NIR fluorophores as labels (in conjunction with immunosensor technology) and the use of NIR chromophores as direct probes (pH, metal ion, etc.). Additionally the use of laser diodes and semiconductor detectors (silicon photodiodes and avalanche photodiodes) as light sources and detectors will be discussed.
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Lawrence Evans III, Guillermo A. Casay, Dong Dai, Gabor Patonay, "Near-infrared fluorescence sensor technology," Proc. SPIE 2504, Environmental Monitoring and Hazardous Waste Site Remediation, (9 October 1995); https://doi.org/10.1117/12.224115