Theoretical feasibility study for wave-mixing near-field optics experiments in biology, chemistry, and materials science

Xiaolin Zhao; Raoul Kopelman

doi:10.1117/12.218687

6 September 1995 Theoretical feasibility study for wave-mixing near-field optics experiments in biology, chemistry, and materials science

Xiaolin Zhao, Raoul Kopelman

Author Affiliations +

Proceedings Volume 2535, Near-Field Optics; (1995) https://doi.org/10.1117/12.218687
Event: SPIE's 1995 International Symposium on Optical Science, Engineering, and Instrumentation, 1995, San Diego, CA, United States

Abstract

Although the advance of near field optics gives us the ability to achieve sub-wavelength resolution in microscopy, so far its application to chemistry and biology has been mostly limited to fluorescence and transmission imaging. In this study we propose a new method, namely using the nonlinear near field optics properties to study the material interactions directly, by wave-mixing the near field and the external pumping field. Using this method, one can study the rich non-linear spectroscopic properties of many systems with the added bonus of near field resolution.

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Xiaolin Zhao and Raoul Kopelman "Theoretical feasibility study for wave-mixing near-field optics experiments in biology, chemistry, and materials science", Proc. SPIE 2535, Near-Field Optics, (6 September 1995); https://doi.org/10.1117/12.218687

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