Photophysical properties of pheophorbide-a in different carrier-systems

Beate Roeder; St. Hackbarth; Olaf Korth; Ralf Herter; Thomas Hanke; Wolfgang Hoehne

doi:10.1117/12.230959

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31 January 1996 Photophysical properties of pheophorbide-a in different carrier-systems

Beate Roeder, St. Hackbarth, Olaf Korth, Ralf Herter, Thomas Hanke, Wolfgang Hoehne

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Proceedings Volume 2625, Photochemotherapy: Photodynamic Therapy and Other Modalities; (1996) https://doi.org/10.1117/12.230959
Event: BiOS Europe '95, 1995, Barcelona, Spain

Abstract

Various tetrapyrrolic compounds are well-known photosensitizers in PDT. One of the important unsolved problems in PDT research is the selective accumulation of such compounds in tumor tissues. In this context different carrier systems for efficacious and directed transport of the dyes to the tumor tissue are still under investigation. From these investigations new problems have arisen like change of the sensitizer's photoactivity and photostability. As a result the relation between energy and electron transfer processes (that means the relative efficacy of sensitization via type I and II) during illumination can change. The photophysical properties of Pheoporbide a in different sensitizer-carrier systems (antibodies and liposomes), are investigated.

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Beate Roeder, St. Hackbarth, Olaf Korth, Ralf Herter, Thomas Hanke, and Wolfgang Hoehne "Photophysical properties of pheophorbide-a in different carrier-systems", Proc. SPIE 2625, Photochemotherapy: Photodynamic Therapy and Other Modalities, (31 January 1996); https://doi.org/10.1117/12.230959

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