Tissue Characterization Using Energy-Selective Computed Tomography

Robert E. Alvarez; William H. Marshall; Roger Lewis

doi:10.1117/12.931817

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16 July 1981 Tissue Characterization Using Energy-Selective Computed Tomography

Robert E. Alvarez, William H. Marshall, Roger Lewis

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Proceedings Volume 0273, Application of Optical Instrumentation in Medicine IX; (1981) https://doi.org/10.1117/12.931817
Event: Application of Optical Instrumentation in Medicine, 1981, San Francisco, United States

Abstract

Energy-selective computed tomography has several important properties useful for in-vivo tissue characterization. Most importantly, it produces more information than conventional computed tomography. This information can be considered to be an added dimension which can be used to eliminate the ambiguities in conventional CT data. The noise in energy-selective computed tomography is also two dimensional and an un-correlated coordinate system can be defined which is needed for studying the capabilities of the technique for characterizing tissues. By using the calibration material basis set, the information from energy-selective CT can be extracted with extreme accuracy. Our preliminary experiments indicate that the technique is accurate enough to characterize the difference between gray and white matter. Most conventional systems have difficulty in distinguishing these materials, much less characterizing the reason for their differing attenuation. Thus energy-selective CT has the promise of providing extremely accurate tissue characterization based on its physical properties.

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Robert E. Alvarez, William H. Marshall, and Roger Lewis "Tissue Characterization Using Energy-Selective Computed Tomography", Proc. SPIE 0273, Application of Optical Instrumentation in Medicine IX, (16 July 1981); https://doi.org/10.1117/12.931817

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