Healing of bone in the rat following surgery with the erbium-YAG laser

Mark Russell Dickinson; Hugh Devlin; Monsour A. El Montaser; Philip Sloan

doi:10.1117/12.260729

5 December 1996 Healing of bone in the rat following surgery with the erbium-YAG laser

Mark Russell Dickinson, Hugh Devlin, Monsour A. El Montaser, Philip Sloan

Proceedings Volume 2923, Laser-Tissue Interaction and Tissue Optics II; (1996) https://doi.org/10.1117/12.260729
Event: BiOS Europe '96, 1996, Vienna, Austria

Abstract

Background and objectives: the aim of this study was to examine the pattern of healing in rat calvarial defects prepared with the erbium-YAG laser, using the 'guided tissue regeneration' technique. Materials and method: PTFE membranes were placed over lased skull defects, and the skin wounds sutured. Rats were killed humanely at intervals after surgery, and the skulls processed for paraffin wax histology. A further group of mature rats were also killed humanely and the calvariae removed. Slots were prepared using the erbium-YAG laser and immediately examined under the environmental scanning electron microscope (ESEM) in hydrated conditions, which avoided drying artifacts. Results: An amorphous, mineral-rich carbon layer surrounds the lased bone defect, which in the in vivo experiments was seen as a basophilic zone which was resistant to resorption.

Citation Download Citation

Mark Russell Dickinson, Hugh Devlin, Monsour A. El Montaser, and Philip Sloan "Healing of bone in the rat following surgery with the erbium-YAG laser", Proc. SPIE 2923, Laser-Tissue Interaction and Tissue Optics II, (5 December 1996); https://doi.org/10.1117/12.260729

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KEYWORDS

Bone

Surgery

Laser therapeutics

Laser vision correction

In vivo imaging

Carbon

In vitro testing

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