GaAs/AlGaAs-based Mach-Zehnder interferometer as integrated optical immunosensor

Bernd Maisenhoelder; Hans P. Zappe; Rino E. Kunz; Peter Riel; Michael Moser; Gert L. Duveneck

doi:10.1117/12.259972

26 November 1996 GaAs/AlGaAs-based Mach-Zehnder interferometer as integrated optical immunosensor

Bernd Maisenhoelder, Hans P. Zappe, Rino E. Kunz, Peter Riel, Michael Moser, Gert L. Duveneck

Proceedings Volume 2928, Biomedical Systems and Technologies; (1996) https://doi.org/10.1117/12.259972
Event: BiOS Europe '96, 1996, Vienna, Austria

Abstract

System miniaturization is a key issue in further development of integrated optical sensors. We present an integrated optical GaAs/AlGaAs-based Mach-Zehnder interferometer with a 2 mm long TiO₂ on SiO₂ embedded waveguide sensor pad and its performance as a bioaffinity sensor. Preliminary experiments to evaluate the performance of our Mach-Zehnder interferometer device were done by studying the binding of immunoglobulin (IgG) to protein A. The current resolution limit of IgG surface coverage is 3 pg/mm², corresponding to less than 1/1600 of a saturated IgG monolayer. Since the design of the basic GaAs/AlGaAs waveguide structure is fully compatible with monolithic integration of lasers, modulators and detectors, improved performance can be expected from integration of these optoelectronic components on the same chip.

Citation Download Citation

Bernd Maisenhoelder, Hans P. Zappe, Rino E. Kunz, Peter Riel, Michael Moser, and Gert L. Duveneck "GaAs/AlGaAs-based Mach-Zehnder interferometer as integrated optical immunosensor", Proc. SPIE 2928, Biomedical Systems and Technologies, (26 November 1996); https://doi.org/10.1117/12.259972

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